Description

2-Methyl-2-(Pyrimidin-2-Yl)Propanenitrile is a high-purity, specialized organic nitrile building block of significant interest in advanced synthetic chemistry. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrimidine-substituted structure enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require pyrimidine-based active components.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its electron-deficient pyrimidine ring.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Methyl-2-(Pyrimidin-2-Yl)Propanenitrile
CAS No.	1849313-91-2
Molecular Formula	C8H9N3
Molecular Weight	147.18 g/mol
Synonyms	2-(1-Cyano-1-methylethyl)pyrimidine; 2-(2-Pyrimidinyl)-2-methylpropionitrile; Propanenitrile, 2-methyl-2-(2-pyrimidinyl)-; α,α-Dimethyl-2-pyrimidineacetonitrile; 2-Pyrimidineacetonitrile, α,α-dimethyl-; 2-(Pyrimidin-2-yl)-2-methylpropanenitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-2-(Pyrimidin-2-Yl)Propanenitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.