Description

Acetonitrile, 2-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]- is a high-value, functionalized acetonitrile derivative containing a key pinacol boronate ester group. This compound matters as a versatile and critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require advanced intermediates for developing new active ingredients. Our supply ensures high purity and batch-to-batch consistency for reliable performance in sensitive synthesis workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated and boronate-containing structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials and polymers.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester moiety makes this compound an ideal partner for palladium-catalyzed coupling with aryl or vinyl halides.
• Chemical Biology & Probe Development: Utilized in creating fluorescent tags, molecular probes, and bioconjugation reagents for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up campaigns.

Basic Information

Item	Detail
Product Name	Acetonitrile, 2-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-
CAS No.	1847480-32-3
Molecular Formula	C16H21BFNO3
Molecular Weight	305.15 g/mol
Synonyms	2-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)acetonitrile; 2-[2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]acetonitrile; 4-(2-Cyanoethoxy)-3-fluorophenylboronic acid pinacol ester; (4-(Cyanomethoxy)-3-fluorophenyl)boronic acid pinacol ester; Acetonitrile, [2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-; PINACOL 2-(2-FLUORO-4-BORONIC ACID PINACOL ESTER PHENOXY)ACETONITRILE
EINECS	Contact for details

Quality Control

Our Acetonitrile, 2-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.