Description

Benzeneacetic Acid, 4-[1-(Trifluoromethyl)Cyclopropyl]- is a high-value, fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopropyl group substituted with a trifluoromethyl moiety, makes it a critical intermediate for creating novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce lipophilicity and metabolic stability into active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in CNS and metabolic disease research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine moiety for enhanced bioactivity.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to materials with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: A valuable synthon for creating fluorinated components in electronic display and lighting technologies.
• Chemical Biology Probes: Utilized in medicinal chemistry to create labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring sophisticated fluorinated architectures.

Basic Information

Product Name	Benzeneacetic Acid, 4-[1-(Trifluoromethyl)Cyclopropyl]-
CAS No.	1838654-62-8
Molecular Formula	C₁₂H₁₁F₃O₂
Molecular Weight	244.21 g/mol
Synonyms	4-[1-(Trifluoromethyl)cyclopropyl]benzeneacetic acid; 2-[4-[1-(Trifluoromethyl)cyclopropyl]phenyl]acetic acid; p-[1-(Trifluoromethyl)cyclopropyl]phenylacetic acid; (4-(1-(Trifluoromethyl)cyclopropyl)phenyl)acetic acid; α-(4-(1-(Trifluoromethyl)cyclopropyl)phenyl)acetic acid; Benzeneacetic acid, 4-(1-(trifluoromethyl)cyclopropyl)-; CAS 1838654-62-8
EINECS	Contact for details

Quality Control

Every batch of our Benzeneacetic Acid, 4-[1-(Trifluoromethyl)Cyclopropyl]- is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.