Description

2-(4-(Benzyloxy)-2-Ethyl-5-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane (Wx192036) is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing fluorinated biaryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in constructing advanced fungicides, herbicides, and insecticides that require specific fluorinated aromatic components.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to synthesize tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital reagent for CROs and CDMOs engaged in bespoke chemical synthesis for client projects.

Basic Information

Product Name	2-(4-(Benzyloxy)-2-Ethyl-5-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane (Wx192036)
CAS No.	1825308-37-9
Molecular Formula	C21H26BFO3
Molecular Weight	356.24 g/mol
Synonyms	2-(4-(Benzyloxy)-2-ethyl-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Benzyloxy)-2-ethyl-5-fluorophenylboronic acid pinacol ester; (4-(Benzyloxy)-2-ethyl-5-fluorophenyl)boronic acid pinacol ester; WX-192036; Wx192036; BRN 1825308-37-9; 2-Ethyl-5-fluoro-4-(phenylmethoxy)benzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-(Benzyloxy)-2-Ethyl-5-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability and consistency for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term storage and during weighing to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.