Description

[(Diphenylphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide is a specialized organophosphorus compound featuring a sulfinamide group, designed for advanced synthetic applications. Its value lies in its dual functionality as a chiral ligand and a building block, enabling precise control in asymmetric catalysis and complex molecule construction. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand or precursor for transition metal catalysts in enantioselective synthesis.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing stereogenic centers.
• Agrochemical Synthesis: Employed as a building block for creating chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science: Acts as a functional monomer or additive in the development of specialized polymers and advanced materials.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings, due to its phosphine moiety.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and process chemistry.

Basic Information

Product Name	[(Diphenylphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1824731-39-6
Molecular Formula	C24H28NOPS
Molecular Weight	409.52 g/mol
Synonyms	(R)- or (S)-tert-Butanesulfinamide derivative; N-[(2-(Diphenylphosphino)phenyl)ethyl]-2-methylpropane-2-sulfinamide; Phosphine-sulfinamide hybrid ligand; Chiral sulfinyl imine precursor; P,N-Ligand; tert-Butylsulfinamide phosphine derivative
EINECS	Contact for details

Quality Control

Every batch of [(Diphenylphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide is produced and tested under strict quality management protocols to ensure consistency and reliability for critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, chiral purity (enantiomeric excess), and key impurity profiles. Our quality systems support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.