Description

n-((3Ar,4S,7S,8R,8Ar)-4-(Hydroxymethyl)-2,2-Dimethylhexahydro-4,7-Epoxy[1,3]Dioxolo[4,5-D]Oxepin-8-Yl)Acetamide is a sophisticated chiral intermediate with a complex bicyclic acetal and epoxide structure. This compound is of significant value for its role in the synthesis of complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or substrate in the development of new asymmetric synthetic methodologies.
• Glycomimetics and Carbohydrate Chemistry: The fused dioxolane-oxepine structure makes it a relevant intermediate for synthesizing complex sugar analogs and glycomimetic drugs.
• Process Chemistry Development: Employed in scaling up synthetic routes for complex molecules, requiring high-purity, well-defined intermediates.
• Academic and Institutional Research: Used in universities and research institutes for exploratory organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	n-((3Ar,4S,7S,8R,8Ar)-4-(Hydroxymethyl)-2,2-Dimethylhexahydro-4,7-Epoxy[1,3]Dioxolo[4,5-D]Oxepin-8-Yl)Acetamide
CAS No.	1824718-03-7
Molecular Formula	C13H21NO6
Molecular Weight	287.31 g/mol
Synonyms	Acetamide, N-[(3aR,4S,7S,8R,8aR)-4-(hydroxymethyl)-2,2-dimethylhexahydro-4,7-epoxy[1,3]dioxolo[4,5-d]oxepin-8-yl]-; (3aR,4S,7S,8R,8aR)-8-Acetamido-4-(hydroxymethyl)-2,2-dimethylhexahydro-4,7-epoxy[1,3]dioxolo[4,5-d]oxepine; Chiral Oxepine Acetamide Derivative; Bicyclic Acetal-Epoxide Intermediate; CAS 1824718-03-7
EINECS	Contact for details

Quality Control

Our n-((3Ar,4S,7S,8R,8Ar)-4-(Hydroxymethyl)-2,2-Dimethylhexahydro-4,7-Epoxy[1,3]Dioxolo[4,5-D]Oxepin-8-Yl)Acetamide is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.