Description

Benzene, 1-Bromo-2-Fluoro-4-Methoxy-3-Methyl- is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern, featuring bromo, fluoro, and methoxy groups on a methylated benzene ring, makes it a valuable intermediate for creating complex molecular architectures. This compound is primarily targeted at research and development chemists in the pharmaceutical, agrochemical, and material science industries who require precise and reliable intermediates for drug discovery, ligand synthesis, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores for bioactivity or as synthetic handles for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance metabolic stability and binding affinity.
• Ligand and Catalyst Development: Acts as a building block for creating sophisticated ligands used in transition metal catalysis, leveraging the methoxy and halogen groups for fine-tuning electronic and steric properties.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or advanced polymers, where its specific substitution pattern can influence material properties like charge transport or mesophase behavior.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems, as the bromine atom offers a site for further cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	Benzene, 1-Bromo-2-Fluoro-4-Methoxy-3-Methyl-
CAS No.	1824307-17-6
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-Bromo-2-fluoro-4-methoxy-3-methylbenzene; 3-Methyl-4-methoxy-2-fluorobromobenzene; 2-Fluoro-4-methoxy-3-methylbromobenzene; 4-Methoxy-3-methyl-2-fluorophenyl bromide; (2-Fluoro-4-methoxy-3-methylphenyl)bromide; Bromo(2-fluoro-4-methoxy-3-methyl)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-2-Fluoro-4-Methoxy-3-Methyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. While produced to general laboratory or technical grade standards, specifications can be discussed for projects requiring adherence to specific guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.