Description

3-Cyanocyclobutanecarboxylic Acid is a versatile and high-purity chemical building block featuring both a carboxylic acid and a nitrile functional group on a strained cyclobutane ring. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical companies for creating novel active ingredients and by academic institutions for exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the strained ring for unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and mechanical properties.
• Material Science Research: Utilized in the development of advanced organic electronic materials and liquid crystals due to its rigid, polar structure.
• Chemical Biology Probes: Acts as a scaffold for designing activity-based probes and molecular tools to study enzyme function and biological pathways.

Basic Information

Product Name	3-Cyanocyclobutanecarboxylic Acid
CAS No.	1823933-75-0
Molecular Formula	C6H7NO2
Molecular Weight	125.13 g/mol
Synonyms	3-Cyanocyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 3-cyano-; 3-Carboxycyclobutanecarbonitrile; 1-Cyanocyclobutane-3-carboxylic Acid; 3-Cyano-1-cyclobutanecarboxylic Acid; 3-Cyanocyclobutane-1-carboxylic Acid; (3-Cyanocyclobutyl)formic acid
EINECS	Contact for details

Quality Control

Our 3-Cyanocyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.