Description

2-Fluoro-5-Iodo-4-Methylanisole is a high-purity, multi-functional halogenated anisole derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated and iodinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the fluorine and iodine atoms for enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials, where its molecular structure contributes to desired dielectric and luminescent properties.
• Cross-Coupling Reactions: Essential substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira) for creating complex biaryl and conjugated systems in medicinal and materials chemistry.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	2-Fluoro-5-Iodo-4-Methylanisole
CAS No.	1823867-60-2
Molecular Formula	C8H8FIO
Molecular Weight	266.05 g/mol
Synonyms	1-Fluoro-2-Iodo-5-Methoxy-4-Methylbenzene; 4-Methyl-2-Fluoro-5-Iodoanisole; 5-Iodo-2-Fluoro-4-Methylanisole; 2-Fluoro-4-Methyl-5-Iodoanisole; 1-Methoxy-2-Fluoro-4-Methyl-5-Iodobenzene; Benzene, 1-fluoro-2-iodo-5-methoxy-4-methyl-; 1823867-60-2
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodo-4-Methylanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.