Description

4-Ethynyl-1-(2-Fluoroethyl)-1H-Pyrazole is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its molecular architecture, featuring both a reactive ethynyl group and a fluoroethyl substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides that require fluorine-containing motifs for enhanced bioactivity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic frameworks (MOFs/COFs).
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and introducing fluorine atoms into complex molecular systems.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis and metal-organic complexes.
• R&D Scale-up: Supplied for process optimization and route scouting from laboratory to pilot plant scale.

Basic Information

Product Name	4-Ethynyl-1-(2-Fluoroethyl)-1H-Pyrazole
CAS No.	1823843-56-6
Molecular Formula	C7H7FN2
Molecular Weight	138.14 g/mol
Synonyms	1-(2-Fluoroethyl)-4-ethynyl-1H-pyrazole; 4-Ethynyl-1-(2-fluoroethyl)pyrazole; 4-Ethynyl-1-(2-fluoroethyl)-1H-pyrazole; 1823843-56-6; 4-Ethynyl-1-(fluoroethyl)pyrazole; 1H-Pyrazole, 4-ethynyl-1-(2-fluoroethyl)-; 4-Ethynyl-1-(2-fluoroethyl)pyrazole
EINECS	Contact for details

Quality Control

Every batch of 4-Ethynyl-1-(2-Fluoroethyl)-1H-Pyrazole is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.