Description

2-Fluoro-4-Methyl-3-(Trifluoromethyl)Phenylacetic Acid CAS NO 1823577-71-4 is a high-value fluorinated aromatic building block. This compound is critical for the synthesis of advanced molecules, offering unique steric and electronic properties due to its trifluoromethyl and fluorine substituents. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, stability, and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance and durability in display technologies.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, or altered surface characteristics.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reactions, catalysis, and the development of novel fluorinated compound libraries.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-4-Methyl-3-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1823577-71-4
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	2-Fluoro-4-methyl-3-(trifluoromethyl)benzeneacetic acid; [2-Fluoro-4-methyl-3-(trifluoromethyl)phenyl]acetic acid; 2-(2-Fluoro-4-methyl-3-(trifluoromethyl)phenyl)acetic acid; α-(2-Fluoro-4-methyl-3-(trifluoromethyl)phenyl)acetic acid; 3-(Trifluoromethyl)-2-fluoro-4-methylphenylacetic acid; FMTFPA; 1823577-71-4
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-4-Methyl-3-(Trifluoromethyl)Phenylacetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.