Description

5-(6-Fluoro-4H-1,3-Benzodioxin-8-Yl)-1,3-Oxazole is a high-purity, advanced pharmaceutical intermediate featuring a fused benzodioxin-oxazole heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and inflammatory pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and anti-inflammatory applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique heterocyclic scaffold.
• Process Chemistry Development: Serves as a critical intermediate for scaling up API synthesis under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Potential use as a molecular probe or ligand in biochemical assays and target validation studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and agrochemical intermediates.

Basic Information

Product Name	5-(6-Fluoro-4H-1,3-Benzodioxin-8-Yl)-1,3-Oxazole
CAS No.	1823272-05-4
Molecular Formula	C11H6FNO3
Molecular Weight	219.17 g/mol
Synonyms	5-(6-Fluoro-4H-benzo[d][1,3]dioxin-8-yl)oxazole; 8-(Oxazol-5-yl)-6-fluoro-4H-1,3-benzodioxine; 5-(6-Fluoro-4H-1,3-benzodioxin-8-yl)oxazole; 1823272-05-4; 6-Fluoro-8-(1,3-oxazol-5-yl)-4H-1,3-benzodioxine; 5-(6-Fluoro-4H-benzo[d][1,3]dioxin-8-yl)-1,3-oxazole; Fluoro-benzodioxinyl oxazole
EINECS	Contact for details

Quality Control

Our 5-(6-Fluoro-4H-1,3-Benzodioxin-8-Yl)-1,3-Oxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports development from research to commercial scale, with the capability to supply material meeting ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.