Description

L-Norleucine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-6-Methoxy- is a specialized, high-purity amino acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in the synthesis of complex peptides and other bioactive molecules, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the controlled, sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the research and development of new active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation and Labeling: Used in the modification of peptides and proteins for diagnostic, imaging, or targeted drug delivery applications.
• Chemical Biology Research: A valuable tool for studying protein-protein interactions, enzyme mechanisms, and metabolic pathways.
• Process Development & Scale-Up: Employed in optimizing synthetic routes for the cost-effective and reliable production of peptide-based therapeutics.

Basic Information

Product Name	L-Norleucine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-6-Methoxy-
CAS No.	1823167-86-7
Molecular Formula	C22H25NO5
Molecular Weight	383.44 g/mol
Synonyms	Fmoc-Nle(6-OMe)-OH; Fmoc-6-Methoxy-L-norleucine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-6-methoxy-L-norleucine; Nα-Fmoc-6-methoxy-L-norleucine; Fmoc-L-Nle(6-OMe)-OH; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-6-methoxyhexanoic acid; Fmoc-6-OMe-L-Nle-OH
EINECS	Contact for details

Quality Control

Our L-Norleucine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-6-Methoxy- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.