Description

3-(4-Bromo-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile brominated pyrazole scaffold for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its reactive bromine and nitrile functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.
• Library Synthesis: Used to create diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	3-(4-Bromo-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile
CAS No.	1822969-98-1
Molecular Formula	C11H14BrN3
Molecular Weight	268.16 g/mol
Synonyms	3-Cyclopentyl-3-(4-bromo-1H-pyrazol-1-yl)propanenitrile; 3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropionitrile; 3-Cyclopentyl-3-(4-bromopyrazol-1-yl)propanenitrile; 1H-Pyrazole-1-propanenitrile, 4-bromo-3-cyclopentyl-; 1822969-98-1; 3-(4-Bromo-pyrazol-1-yl)-3-cyclopentyl-propionitrile
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.