Description

3-Iodo-n-Cbz-Dl-Alanine Methyl Ester is a protected, iodinated amino acid derivative designed for advanced organic synthesis. This compound is a critical building block for the preparation of modified peptides and complex bioactive molecules, offering a reactive iodine handle for cross-coupling reactions. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents and specialized chemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of iodinated peptide analogs and potential drug candidates.
• Chemical Biology Probes: Used to incorporate iodine atoms into peptides for labeling, structural studies, or as handles for further bioconjugation.
• Cross-Coupling Reactions: The iodine atom serves as an excellent leaving group for palladium-catalyzed reactions like Suzuki, Sonogashira, or Heck couplings to create diverse carbon-carbon bonds.
• Protecting Group Chemistry: The Cbz (carboxybenzyl) group provides orthogonal protection for the amine functionality, allowing for selective deprotection in multi-step syntheses.
• Academic & Industrial Research: Essential reagent for exploring new synthetic methodologies and constructing complex molecular architectures in R&D laboratories.

Basic Information

Product Name	3-Iodo-n-Cbz-Dl-Alanine Methyl Ester
CAS No.	1822420-54-1
Molecular Formula	C12H14INO4
Molecular Weight	363.15 g/mol
Synonyms	Methyl 2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate; N-Carbobenzoxy-3-iodo-DL-alanine methyl ester; Cbz-3-Iodo-DL-Ala-OMe; (RS)-Methyl 2-((benzyloxycarbonyl)amino)-3-iodopropanoate; 3-Iodo-N-(benzyloxycarbonyl)-DL-alanine methyl ester; Z-3-Iodo-DL-Ala-OMe; Nα-Cbz-3-iodo-DL-alanine methyl ester; Benzyl (1-methoxy-1-oxo-3-iodopropan-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our 3-Iodo-n-Cbz-Dl-Alanine Methyl Ester is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.