Description

(1S,3R)-3-Acetamidocyclohexane-1-Carboxylic acid is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclohexane backbone functionalized with both acetamide and carboxylic acid groups, making it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.
• Peptidomimetic Scaffold: Serves as a constrained, non-natural amino acid analog for designing bioactive peptides with enhanced stability and selectivity.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: Employed in chemical biology and medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Acts as a specialized starting material for the synthesis of high-value agrochemicals and specialty chemicals.

Basic Information

Product Name	(1S,3R)-3-Acetamidocyclohexane-1-Carboxylic Acid
CAS No.	1821748-41-7
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	(1S,3R)-3-Acetamidocyclohexanecarboxylic Acid; (1S,3R)-3-(Acetylamino)cyclohexanecarboxylic Acid; trans-3-Acetamidocyclohexanecarboxylic Acid (specific isomer); 3-Acetamidocyclohexane-1-carboxylic acid (1S,3R)-; AC1L4BQK; AKOS040745176; ZINC000070046717; (1S,3R)-rel-3-Acetamidocyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of (1S,3R)-3-Acetamidocyclohexane-1-Carboxylic acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing purity, chiral purity, and impurity profile data is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.