Description

2-Chloro-4-Ethoxy-5-Iodobenzonitrile is a halogenated benzonitrile derivative, a versatile and high-value organic intermediate in advanced chemical synthesis. Its molecular structure, featuring chloro, ethoxy, and iodo substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of molecular tools for biological research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Chloro-4-Ethoxy-5-Iodobenzonitrile
CAS No.	1819332-89-2
Molecular Formula	C9H7ClINO
Molecular Weight	307.52 g/mol
Synonyms	5-Iodo-2-chloro-4-ethoxybenzonitrile; 2-Chloro-4-ethoxy-5-iodobenzonitrile; Benzonitrile, 2-chloro-4-ethoxy-5-iodo-; 4-Ethoxy-5-iodo-2-chlorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Ethoxy-5-Iodobenzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.