Description

3-Aminooxetane-3-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique oxetane ring system. This compound matters as a versatile building block for medicinal chemistry, enabling the synthesis of novel drug candidates with improved metabolic stability and pharmacokinetic properties. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry: Used as a bioisostere to replace traditional functional groups, enhancing the drug-like properties of lead compounds, such as solubility and metabolic stability.
• Process Chemistry & Scale-up: Serves as a critical starting material for the optimization and commercial-scale production of candidate drugs.
• Chemical Biology Probes: Utilized in the synthesis of specialized molecules for studying biological pathways and target engagement.
• Agrochemical Research: Potential application as a building block in the discovery of new crop protection agents with novel modes of action.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for exploratory synthetic chemistry and method development.

Basic Information

Product Name	3-Aminooxetane-3-Carbonitrile Hydrochloride
CAS No.	1818847-73-2
Molecular Formula	C4H7N3O·HCl
Molecular Weight	149.58 g/mol (Free base: 113.12 g/mol)
Synonyms	3-Amino-3-cyanoxetane hydrochloride; 3-Aminooxetane-3-carbonitrile HCl; 3-Cyano-3-aminooxetane hydrochloride; Oxetan-3-amine-3-carbonitrile hydrochloride; 3-Aminoxetane-3-carbonitrile hydrochloride; 3-Amino-3-cyanooxetane hydrochloride; 3-Oxetanamine-3-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Aminooxetane-3-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.