Description

7-(Trifluoromethyl)-3-Azabicyclo[4.1.0]Heptane Hydrochloride is a high-value, advanced pharmaceutical intermediate featuring a unique bicyclic scaffold with a trifluoromethyl group. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for creating potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Protease Inhibitor Development: The bicyclic amine structure is valuable for designing inhibitors of various enzymatic targets.
• Agrochemical Synthesis: Serves as a precursor for developing advanced crop protection agents with improved efficacy.
• Ligand and Catalyst Preparation: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorinated Compound Libraries: An essential component for creating focused libraries of fluorinated compounds in drug discovery.

Basic Information

Product Name	7-(Trifluoromethyl)-3-Azabicyclo[4.1.0]Heptane Hydrochloride
CAS No.	1818847-27-6
Molecular Formula	C8H11ClF3N
Molecular Weight	213.63 g/mol
Synonyms	3-Azabicyclo[4.1.0]heptane, 7-(trifluoromethyl)-, hydrochloride (1:1); 7-(Trifluoromethyl)-3-azabicyclo[4.1.0]heptane HCl; 7-(Trifluoromethyl)-3-azabicyclo[4.1.0]heptane hydrochloride; 7-(Trifluoromethyl)-3-azabicyclo[4.1.0]heptane monohydrochloride; 3-Azabicyclo[4.1.0]heptane, 7-(trifluoromethyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality management and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.