Description

C5A Anaphylatoxin (Human) is a potent bioactive peptide fragment derived from the complement component C5, playing a critical role in inflammatory and immune responses. This high-purity reference standard is essential for researchers and developers requiring precise and reliable materials for mechanistic studies and assay development. It is primarily utilized in pharmaceutical R&D, immunology research, and the development of diagnostic kits targeting complement-mediated pathways.

Application

• Biomedical Research: Used as a key reference standard in studying the complement system, inflammation mechanisms, and anaphylatoxin receptor (C5aR) signaling pathways.
• Drug Discovery & Development: Serves as a critical tool for screening and validating potential therapeutic inhibitors targeting the C5a/C5aR axis for inflammatory and autoimmune diseases.
• Diagnostic Assay Development: Employed in the calibration and quality control of ELISA kits and other immunoassays designed to detect complement activation products.
• In Vitro & Ex Vivo Studies: Applied in cell-based assays to induce and model inflammatory responses in neutrophils, macrophages, and other immune cells.
• Quality Control & Standardization: Acts as a purity standard for the manufacturing and batch release testing of related biopharmaceutical products.

Basic Information

Product Name	C5A Anaphylatoxin (Human)
CAS No.	1816940-05-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	C5a anaphylatoxin (human); Complement C5a; C5a; Anaphylatoxin C5a, human; C5a des-Arg; Complement component 5a; C5a fragment
EINECS	Contact for details

Quality Control

Our C5A Anaphylatoxin (Human) is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and bioactivity. We adhere to relevant guidelines for research-grade biochemicals to support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -70°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Determined by functional assay (e.g., calcium flux, chemotaxis)
Endotoxin Level	< 1.0 EU/μg
Water Content (K.F.)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.