Description

Bnp (1-45), Mouse is a synthetic peptide fragment corresponding to the N-terminal region of the mouse Brain Natriuretic Peptide (BNP). This high-purity biochemical is essential for cardiovascular and neuroendocrine research, providing a critical tool for studying BNP signaling pathways and receptor interactions in murine models. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on heart failure, hypertension, and biomarker discovery.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of natriuretic peptide systems, cardiac function, and fluid homeostasis.
• Assay Development: Serves as a critical calibrant and immunogen in the development and validation of ELISA, RIA, and other immunoassays for detecting mouse BNP.
• Receptor Binding Studies: Employed in competitive binding assays to characterize the affinity and specificity of the natriuretic peptide receptor-A (NPR-A) and other related receptors.
• Cell Signaling Research: Applied in in vitro cell culture models to investigate downstream signaling cascades, including cGMP production, activated by BNP.
• Pharmaceutical Screening: Acts as a positive control or target molecule in high-throughput screening (HTS) campaigns for novel cardiovascular therapeutics.

Basic Information

Product Name	Bnp (1-45), Mouse
CAS No.	1816939-52-2
Molecular Formula	C212H347N67O63S2
Molecular Weight	4768.5 g/mol
Synonyms	Mouse BNP (1-45); Murine Brain Natriuretic Peptide (1-45); BNP1-45 (Mouse); Brain Natriuretic Peptide 1-45 Mouse; H-Ser-Pro-Lys-Thr-Met-Arg-Asp-Ser-Gly-Cys-Phe-Gly-Arg-Arg-Leu-Asp-Arg-Ile-Gly-Ser-Leu-Ser-Gly-Leu-Gly-Cys-Asn-Val-Leu-Arg-Arg-Tyr-OH (Disulfide bridge: Cys10-Cys26); BNP Mouse Fragment; Natriuretic Peptide B (1-45) Mouse
EINECS	Contact for details

Quality Control

Every batch of Bnp (1-45), Mouse is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Identity is confirmed by Mass Spectrometry (MS) and co-elution with a reference standard via HPLC. Purity is guaranteed by HPLC (≥95%) and correct amino acid sequence is verified. A detailed Certificate of Analysis (COA) including data for purity, content, and residual solvents is provided with each shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. Aliquot into single-use vials after reconstitution to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ±10% of theoretical composition
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.