Description

Biotinyl-α-Cgrp (Mouse, Rat) CAS NO 1816258-61-3 is a high-purity, biotinylated peptide analog specifically designed for advanced biochemical and pharmacological research. This compound is a critical reagent for studying the calcitonin gene-related peptide (CGRP) receptor system, a key target in pain and migraine research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies specializing in neuroscience, cardiovascular studies, and receptor-ligand interaction assays.

Application

• Biochemical Research: As a labeled ligand for the detection, quantification, and characterization of CGRP receptors in binding assays and affinity studies.
• Neuroscience & Pain Research: A vital tool for investigating the role of the CGRP pathway in migraine pathophysiology, neurogenic inflammation, and pain transmission.
• Diagnostic Development: Used in the development of sensitive immunoassays (e.g., ELISA) and imaging probes for CGRP-related biomarkers.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and validate novel antagonists or modulators of the CGRP receptor.
• Receptor Mapping: Facilitates the study of receptor localization, density, and internalization in cell-based and tissue samples via avidin-biotin complex techniques.
• Cardiovascular Research: Applied in studies exploring the vasodilatory effects and regulatory functions of CGRP in the vascular system.

Basic Information

Item	Detail
Product Name	Biotinyl-α-Cgrp (Mouse, Rat)
CAS No.	1816258-61-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-α-CGRP (mouse, rat); Biotinylated α-Calcitonin Gene-Related Peptide (mouse, rat); Biotin-CGRP; Biotin-conjugated CGRP; Biotin-Labeled CGRP Fragment; α-CGRP (mouse, rat) Biotin conjugate; CGRP Biotinylated Analog
EINECS	Contact for details

Quality Control

Every batch of Biotinyl-α-Cgrp (Mouse, Rat) is manufactured and analyzed under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting specifications. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO, or buffer systems

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.