Description

Biotinyl-Neuropeptide W-23 (Human) Trifluoroacetate Salt is a high-purity, biotin-labeled derivative of the neuropeptide W-23, designed for advanced biochemical and pharmacological research. This modification is critical for detection, isolation, and quantification studies, enabling researchers to trace and study the peptide's interactions with its receptors. It is an essential tool for scientists in neuroscience, metabolic disorder research, and drug discovery programs focused on the NPBWR1 and NPBWR2 receptor systems.

Application

• Biomarker Discovery & Proteomics: Used as a tagged ligand in pull-down assays and affinity chromatography to identify and isolate interacting proteins and receptor complexes.
• Receptor Binding & Pharmacological Assays: Essential for competitive binding studies, receptor mapping, and determining binding affinity (Kd) for the NPBW receptors.
• Immunoassay Development: Serves as a standardized antigen or labeled competitor in the development of ELISA and other immunoassays for quantifying Neuropeptide W.
• Cell Signaling & Imaging Studies: Employed in fluorescence-activated cell sorting (FACS) and microscopy when conjugated with streptavidin-fluorophore complexes to visualize receptor localization and internalization.
• Metabolic & Neuroendocrine Research: A key reagent for investigating the role of Neuropeptide W in regulating food intake, energy homeostasis, stress responses, and hormone secretion.
• Quality Control & Reference Standard: Acts as a critical reference material for the quality control of related therapeutic peptides and assay kits.

Basic Information

Product Name	Biotinyl-Neuropeptide W-23 (Human) Trifluoroacetate Salt
CAS No.	1815618-09-7
Molecular Formula	C148H238N44O41S • xC2HF3O2
Molecular Weight	~3328.8 g/mol (Free base)
Synonyms	Biotin-NPW-23; Biotinylated-Neuropeptide W-23 (human); Biotin-Neuropeptide W (23-45), human; Biotinyl-NPW-23; Biotin-NPW23; H-Biotinyl-Ser-Pro-Leu-Pro-Leu-Pro-Arg-Gly-Arg-Asn-Gly-Phe-Phe-Leu-Phe-Met-Pro-Arg-Tyr-NH2 TFA salt; NPW-23 (human), Biotinylated; Biotin-labeled Neuropeptide W-23
EINECS	Contact for details

Quality Control

Every batch of Biotinyl-Neuropeptide W-23 (Human) Trifluoroacetate Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with standards expected for research-grade biochemicals. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, molecular weight confirmation by Mass Spectrometry, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and exposure to humidity. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 8.0%
Acetate Content (HPIC)	≤ 15.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.