Description

Biotinyl-Angiotensin I/II (1-7) is a biotin-labeled peptide fragment derived from the angiotensin sequence, designed for high-affinity binding and detection applications. This modified peptide is critical for researchers requiring precise, non-radioactive tracking of angiotensin-related biological pathways and receptor studies. It is primarily utilized in biochemical research, diagnostic assay development, and pharmaceutical discovery for cardiovascular and renal system investigations.

Application

• Biochemical Research: Used as a labeled probe for studying angiotensin-converting enzyme (ACE) activity, receptor binding assays, and signal transduction mechanisms.
• Diagnostic Development: Serves as a key component in the development of ELISA, Western blot, and other immunoassay kits for detecting angiotensin peptides.
• Pharmaceutical Discovery: Employed in high-throughput screening (HTS) and target validation for drug candidates targeting the renin-angiotensin system (RAS).
• Affinity Purification: Utilized in pull-down assays and streptavidin-biotin interaction systems to isolate and purify specific proteins or complexes.
• Cell Biology Studies: Applied in fluorescence microscopy and flow cytometry for visualizing receptor localization and internalization.
• Proteomics: Acts as a tagged substrate for enzyme kinetic studies and profiling protease specificity within metabolic pathways.

Basic Information

Product Name	Biotinyl-Angiotensin I/II (1-7)
CAS No.	1815618-05-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-Angiotensin (1-7); Biotinylated Angiotensin I/II fragment; Angiotensin I/II (1-7)-biotin; Biotinyl-DRVYIHP; Biotin-labeled Angiotensin heptapeptide; Biotin-Ang (1-7); [Biotinyl]Angiotensin I/II (1-7)
EINECS	Contact for details

Quality Control

Our Biotinyl-Angiotensin I/II (1-7) is manufactured under strict quality protocols suitable for research and development. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.