Description

Acetyl-Acth (3-24) (Human, Bovine, Rat) is a synthetic peptide fragment of adrenocorticotropic hormone (ACTH) that has been acetylated at the N-terminus. This modification is crucial for enhancing its stability and biological activity in research applications, particularly in studies of the hypothalamic-pituitary-adrenal (HPA) axis. It is an essential biochemical tool for researchers and developers in the fields of endocrinology, neuroscience, and pharmaceutical discovery. The compound is supplied under the CAS registry number 1815617-99-2.

Application

• Endocrine Research: Fundamental studies on ACTH receptor binding, signal transduction, and steroidogenesis.
• Neuroscience Models: Investigating stress response pathways, behavioral effects, and HPA axis regulation in animal models.
• Biomarker Development: Utilized as a standard or calibrant in immunoassay development for measuring ACTH-related peptides.
• Drug Discovery: Screening for modulators of the melanocortin receptor system and developing novel therapeutic agents.
• Veterinary Science: Research into adrenal function and stress physiology in bovine and other animal species.
• Academic & Institutional Research: A key reagent for university and government laboratory studies in physiology and molecular biology.

Basic Information

Product Name	Acetyl-Acth (3-24) (Human, Bovine, Rat)
CAS No.	1815617-99-2
Molecular Formula	C112H165N31O34S
Molecular Weight	2494.8 g/mol
Synonyms	Acetyl-ACTH (3-24); N-Acetyl-ACTH (3-24); Acetylated Adrenocorticotropic Hormone Fragment 3-24; Ac-ACTH(3-24); Acetyl-ACTH (human, bovine, rat); Melanocortin receptor ligand; Corticotropin (3-24) acetate; Synthetic ACTH analog
EINECS	Contact for details

Quality Control

Every batch of Acetyl-Acth (3-24) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research applications. A Certificate of Analysis (COA) detailing purity (by HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.