Description

2-(Methylthio)-7Ah-Cyclopenta[D]Pyrimidine-7-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopentapyrimidine core. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncological Agent Synthesis: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies due to its pyrimidine-based structure.
• Antiviral Drug Development: Serves as a starting material for creating nucleotide/nucleoside analogs and other compounds with potential antiviral activity.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(Methylthio)-7Ah-Cyclopenta[D]Pyrimidine-7-Carbonitrile
CAS No.	1812188-57-0
Molecular Formula	C9H7N3S
Molecular Weight	189.24 g/mol
Synonyms	2-(Methylthio)-7aH-cyclopenta[d]pyrimidine-7-carbonitrile; 7aH-Cyclopenta[d]pyrimidine-7-carbonitrile, 2-(methylthio)-; 2-Methylsulfanyl-7aH-cyclopenta[d]pyrimidine-7-carbonitrile; Cyclopentapyrimidine-7-carbonitrile derivative; 2-(Methylmercapto)cyclopentapyrimidine-7-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)-7Ah-Cyclopenta[D]Pyrimidine-7-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.