Description

2-(2,2,2-Trifluoroethyl)-2,6-Diazaspiro[3.3]heptane Ditrifluoroacetate is a high-value, fluorinated spirocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced agrochemical industries who require reliable, high-purity intermediates to accelerate drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides with fluorinated motifs for enhanced efficacy.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological targets and pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Employed in route scouting and scale-up synthesis for clinical trial material (CTM) and commercial API manufacturing.
• Ligand and Catalyst Development: Potential precursor for novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(2,2,2-Trifluoroethyl)-2,6-Diazaspiro[3.3]heptane Ditrifluoroacetate
CAS No.	1810069-99-8
Molecular Formula	C11H12F9N2O4
Molecular Weight	416.22 g/mol
Synonyms	2,6-Diazaspiro[3.3]heptane, 2-(2,2,2-trifluoroethyl)-, ditrifluoroacetate; 2-(2,2,2-Trifluoroethyl)-2,6-diazaspiro[3.3]heptane bis(trifluoroacetate); 2-(Trifluoroethyl)-2,6-diazaspiro[3.3]heptane ditrifluoroacetate; 2,6-Diazaspiro[3.3]heptane, 2-(trifluoroethyl)-, ditrifluoroacetate; 1810069-99-8; TFEDAH Ditrifluoroacetate; Spirocyclic Amine Trifluoroacetate Salt
EINECS	Contact for details

Quality Control

Every batch of 2-(2,2,2-Trifluoroethyl)-2,6-Diazaspiro[3.3]heptane Ditrifluoroacetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.