Description

(R)-(+)-7-[n-(2-Phenylthio)Ethylamino]-7'-[Diphenylphosphino]-2,2',3,3'-Tetrahydro-1,1'-Spirobindane, 97+% (>99% Ee) [(R)-Ph-Spirosap-Ph] is a high-purity, enantiomerically enriched chiral ligand and organocatalyst. This compound is critical for enabling highly selective asymmetric synthesis in advanced pharmaceutical and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex chiral molecules with precise stereocontrol.

Application

• Asymmetric Catalysis: As a chiral ligand in transition metal-catalyzed reactions such as hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediates: Synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Methodology Development: Use in academic and industrial research for developing new asymmetric synthetic protocols.
• Agrochemical Synthesis: Production of chiral herbicides, fungicides, and pesticides with enhanced biological activity.
• Material Science: Potential application in the synthesis of chiral polymers or advanced functional materials.
• Organocatalysis: Acting as a chiral organocatalyst in various carbon-carbon and carbon-heteroatom bond-forming reactions.

Basic Information

Product Name	(R)-(+)-7-[n-(2-Phenylthio)Ethylamino]-7'-[Diphenylphosphino]-2,2',3,3'-Tetrahydro-1,1'-Spirobindane, 97+% (>99% Ee) [(R)-Ph-Spirosap-Ph]
CAS No.	1809609-40-2
Molecular Formula	C39H38NPS
Molecular Weight	583.77 g/mol
Synonyms	(R)-Ph-SpiroSAP-Ph; (R)-7-[2-(Phenylthio)ethylamino]-7'-diphenylphosphino-1,1'-spirobiindane; (R)-Spiro-SAP-Ph Ligand; (R)-7-(2-(Phenylthio)ethylamino)-7'-diphenylphosphino-2,2',3,3'-tetrahydro-1,1'-spirobiindane; (R)-SPIROSAP-Ph; (R)-(+)-Spiro-SAP-Ph; (R)-Chiral Spiro Aminophosphine Ligand; (R)-7-Amino-7'-phosphino Spirobiindane Derivative
EINECS	Contact for details

Quality Control

Our (R)-Ph-SpiroSAP-Ph is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and chiral analysis, to confirm identity, chemical purity (≥97%), and enantiomeric excess (>99% ee). Certificates of Analysis (COA) with full analytical data are provided to support your GMP and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97%
Enantiomeric Excess (Chiral HPLC)	> 99%
Water Content (KF)	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.