Description

2,3-Difluoro-4-Methoxybenzeneboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to construct complex, fluorinated aromatic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluoromethoxy and related motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the fluorinated aromatic structure enhances biological activity and stability.
• Material Science Research: Serves as a precursor for creating fluorinated organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	2,3-Difluoro-4-Methoxybenzeneboronic Acid Pinacol Ester
CAS No.	1809298-92-7
Molecular Formula	C₁₄H₁₉BF₂O₃
Molecular Weight	284.11 g/mol
Synonyms	2,3-Difluoro-4-methoxyphenylboronic acid pinacol ester; (2,3-Difluoro-4-methoxyphenyl)boronic acid pinacol ester; 4-Methoxy-2,3-difluorobenzeneboronic acid pinacol ester; Pinacol (2,3-difluoro-4-methoxyphenyl)boronate; 2,3-Difluoro-4-methoxybenzeneboronic acid, pinacol ester; B-(2,3-Difluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1809298-92-7
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Methoxybenzeneboronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. We ensure high lot-to-lot consistency and purity through advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.