Description

1-Fluoro-3-Ethoxy-5-Methylbenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique substitution pattern enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and alkoxy functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and durability.
• Polymer & Resin Modifier: Employed to introduce fluorine into polymer chains, enhancing properties like chemical resistance, thermal stability, and surface characteristics in high-performance plastics and coatings.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions for constructing complex biaryl systems.
• Chemical Research & Development: Utilized in academic and industrial R&D labs as a versatile reagent for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	1-Fluoro-3-Ethoxy-5-Methylbenzene
CAS No.	1809158-02-8
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	3-Ethoxy-5-fluorotoluene; 5-Fluoro-3-ethoxytoluene; 1-Ethoxy-3-fluoro-5-methylbenzene; 3-Fluoro-5-ethoxytoluene; 5-Methyl-3-ethoxyfluorobenzene; 3-Ethoxy-5-methylfluorobenzene; Benzene, 1-ethoxy-3-fluoro-5-methyl-; 1809158-02-8
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Ethoxy-5-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.