Description

4-(4-Bromophenyl)Piperidine-4-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate of significant interest in modern organic synthesis. This compound is valued for its unique piperidine-carbonitrile scaffold, which serves as a critical building block for the development of novel bioactive molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, process development, and the synthesis of potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale manufacturing of target molecules.
• Academic & Institutional Research: Used in universities and research institutes for synthetic methodology development and novel compound exploration.

Basic Information

Product Name	4-(4-Bromophenyl)Piperidine-4-Carbonitrile Hydrochloride
CAS No.	1809152-76-8
Molecular Formula	C12H12BrN2•HCl
Molecular Weight	300.60 g/mol (Free base: 264.14 g/mol)
Synonyms	4-(4-Bromophenyl)-4-cyanopiperidine hydrochloride; 4-(4-Bromophenyl)piperidine-4-carbonitrile HCl; 4-Cyano-4-(4-bromophenyl)piperidine hydrochloride; 1-(4-Bromophenyl)-4-cyanopiperidinium chloride; 4-(p-Bromophenyl)-4-cyanopiperidine hydrochloride; 4-(4-Bromophenyl)-4-piperidinecarbonitrile hydrochloride; Piperidine-4-carbonitrile, 4-(4-bromophenyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our production of 4-(4-Bromophenyl)Piperidine-4-Carbonitrile Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support compliance with cGMP standards for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.