Description

Sparc-Related Modular Calcium-Binding Protein 2 is a specialized biochemical reagent with a CAS number of 1809068-70-9, playing a crucial role in cellular calcium signaling and matrix interaction pathways. This protein is essential for researchers and developers in life sciences, offering a high-purity tool for investigating bone metabolism, tissue remodeling, and related disease mechanisms. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in target validation and preclinical studies for metabolic and connective tissue disorders.

Application

• Biochemical Research: Used as a critical reagent in studies of calcium-dependent signaling cascades and extracellular matrix biology.
• Target Identification & Validation: Serves as a protein target in drug discovery pipelines for osteoporosis, fibrosis, and cardiovascular diseases.
• Diagnostic Development: Employed in the development of immunoassays and biomarker detection kits for conditions involving abnormal tissue calcification.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study its role in osteoblast differentiation, angiogenesis, and wound healing processes.
• Protein-Protein Interaction Studies: Utilized to investigate binding partners and functional complexes within cellular signaling networks.
• Recombinant Protein Standard: Acts as a purity standard and control in the production and quality control of related recombinant proteins.

Basic Information

Product Name	Sparc-Related Modular Calcium-Binding Protein 2
CAS No.	1809068-70-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SMOC-2; SPARC-related modular calcium-binding protein 2; Testican-3; EFEMP2; FBLN-4; Fibulin-4; MBP-25; Extracellular matrix protein 2; BM-40 family protein
EINECS	Contact for details

Quality Control

Our Sparc-Related Modular Calcium-Binding Protein 2 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive suite of analytical techniques including SDS-PAGE, HPLC, and mass spectrometry to confirm purity, identity, and absence of endotoxins. A Certificate of Analysis (COA) detailing specific results for each lot is provided, supporting compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (SDS-PAGE)	> 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Contact for details
Protein Content (BCA)	> 90%
Solubility	Soluble in PBS or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.