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(2,4-Difluoro-6-Methoxyphenyl)Boronic Acid CAS NO 1808997-86-5


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CAS No.:1808997-86-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2,4-Difluoro-6-Methoxyphenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its role as a key building block in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is critically needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that benefit from the stability and bioactivity of the difluoromethoxyphenyl moiety.
  • Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
  • Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development and the synthesis of complex, fluorinated organic molecules.
  • Ligand Synthesis: Used to prepare specialized boronic acid-based ligands for catalysis and molecular recognition applications.
  • Diagnostic Reagent Precursor: Acts as a starting material for synthesizing probes and sensors used in biochemical assays and imaging.

Basic Information

Product Name (2,4-Difluoro-6-Methoxyphenyl)Boronic Acid
CAS No. 1808997-86-5
Molecular Formula C7H7BF2O3
Molecular Weight 187.94 g/mol
Synonyms 2,4-Difluoro-6-methoxybenzeneboronic acid; (2,4-Difluoro-6-methoxyphenyl)boronic acid; B-(2,4-Difluoro-6-methoxyphenyl)boronic acid; 6-Methoxy-2,4-difluorophenylboronic acid; 2,4-Difluoro-6-methoxybenzeneboronic Acid; (2,4-Difluoro-6-methoxyphenyl)boronic acid (contains varying amounts of Anhydride); 2,4-Difluoro-6-methoxybenzeneboronic acid (contains varying amounts of Anhydride)
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Quality Control

Our (2,4-Difluoro-6-Methoxyphenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality systems are designed to meet the stringent requirements of cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and moisture-sensitive; allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Heavy Metals ≤20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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