Description

Bis(3-Trifluoromethylphenyl)(3-Carboxyphenyl)Phosphine CAS NO 1808959-38-7 is a specialized organophosphorus ligand featuring both electron-withdrawing trifluoromethyl groups and a carboxylic acid functional group. This unique structure makes it a highly valuable precursor for constructing sophisticated catalysts in advanced organic synthesis and materials science. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel catalytic systems.

Application

• Catalyst Ligand for Cross-Coupling Reactions: Serves as a key ligand in palladium- or nickel-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig amination for constructing complex molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated motifs.
• Agrochemical Product Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Advanced Material Precursor: Acts as a building block for functionalized polymers, metal-organic frameworks (MOFs), and other specialty materials.
• Asymmetric Catalysis Research: Investigated as a chiral ligand or a precursor for chiral ligands in enantioselective synthesis.
• Surface Modification Agent: The carboxylic acid group allows for attachment to metal oxides or other surfaces, creating functionalized interfaces.

Basic Information

Product Name	Bis(3-Trifluoromethylphenyl)(3-Carboxyphenyl)Phosphine
CAS No.	1808959-38-7
Molecular Formula	C22H13F6O2P
Molecular Weight	460.31 g/mol
Synonyms	(3-Carboxyphenyl)bis[3-(trifluoromethyl)phenyl]phosphine; [3-(Bis[3-(trifluoromethyl)phenyl]phosphino)benzoic acid]; 3-(Bis(3-(trifluoromethyl)phenyl)phosphino)benzoic acid; Phosphine, [3-(carboxyphenyl)]bis[3-(trifluoromethyl)phenyl]-; Bis(3-trifluoromethylphenyl)(3-carboxyphenyl)phosphine ligand
EINECS	Contact for details

Quality Control

Our Bis(3-Trifluoromethylphenyl)(3-Carboxyphenyl)Phosphine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.