Description

Bis(4-Trifluoromethylphenyl)(4-Carboxyphenyl)Phosphine CAS NO 1808959-36-5 is a specialized organophosphorus compound featuring a phosphine core flanked by electron-withdrawing trifluoromethylphenyl groups and a reactive carboxyphenyl substituent. This unique structure makes it a highly valuable ligand and building block in advanced catalytic systems and materials science. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel synthetic methodologies and functional materials.

Application

• As a specialized ligand in transition metal catalysis, particularly for cross-coupling reactions (e.g., Suzuki, Heck) requiring electron-deficient systems.
• Key precursor or intermediate in the synthesis of advanced organic electronic materials, such as OLEDs and OFETs.
• Building block for constructing functionalized phosphine frameworks used in asymmetric catalysis and organometallic chemistry.
• Utilized in pharmaceutical research for the development of novel active pharmaceutical ingredients (APIs) and complex molecules.
• Component in the synthesis of agrochemicals and other fine chemicals where fluorinated phosphine ligands offer unique reactivity.
• Research chemical for studying structure-activity relationships (SAR) and photophysical properties of phosphine-containing compounds.

Basic Information

Product Name	Bis(4-Trifluoromethylphenyl)(4-Carboxyphenyl)Phosphine
CAS No.	1808959-36-5
Molecular Formula	C21H11F6O2P
Molecular Weight	440.28 g/mol
Synonyms	[4-(Bis[4-(trifluoromethyl)phenyl]phosphino)benzoic acid]; (4-Carboxyphenyl)bis[4-(trifluoromethyl)phenyl]phosphine; Phosphine, [4-[bis[4-(trifluoromethyl)phenyl]phosphino]benzoic acid]; Bis(p-trifluoromethylphenyl)(p-carboxyphenyl)phosphine
EINECS	Contact for details

Quality Control

Our Bis(4-Trifluoromethylphenyl)(4-Carboxyphenyl)Phosphine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Elemental Analysis	Conforms to theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.