Description

2-[(R)-[[(R)-(1,1-Dimethylethyl)Sulfinyl]Amino](Phenyl)Methyl]-6-(Diphenylphosphino)-N,n-Diisopropylbenzamide is a sophisticated chiral ligand and organocatalyst, pivotal for enabling highly selective asymmetric synthesis. Its core value lies in its unique bifunctional structure, combining a chiral sulfinamide group with a diphenylphosphino moiety, which allows for precise stereochemical control in critical bond-forming reactions. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and hydroformylation.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond formation.
• Critical intermediate in the research and development of pharmaceutical candidates, particularly for creating single enantiomer drugs.
• Use in academic and industrial R&D for methodology development in asymmetric synthesis.
• Potential application in the synthesis of agrochemicals and other chiral fine chemicals requiring high optical purity.
• Tool compound for studying stereoselective catalysis mechanisms and ligand design.

Basic Information

Product Name	2-[(R)-[[(R)-(1,1-Dimethylethyl)Sulfinyl]Amino](Phenyl)Methyl]-6-(Diphenylphosphino)-N,n-Diisopropylbenzamide
CAS No.	1808268-50-9
Molecular Formula	C38H45N2O2PS
Molecular Weight	624.82 g/mol
Synonyms	(R)-2-[(R)-(tert-Butylsulfinylamino)(phenyl)methyl]-6-(diphenylphosphino)-N,N-diisopropylbenzamide; (R,R)-2-[(tert-Butylsulfinylamino)(phenyl)methyl]-6-(diphenylphosphino)-N,N-diisopropylbenzamide; Chiral Sulfinamide-Phosphine Hybrid Ligand; N,N-Diisopropyl-2-[(R)-(R)-(tert-butylsulfinylamino)(phenyl)methyl]-6-(diphenylphosphino)benzamide; CAS 1808268-50-9; Benzamide, 2-[(R)-[[(R)-(1,1-dimethylethyl)sulfinyl]amino](phenyl)methyl]-6-(diphenylphosphino)-N,N-diisopropyl-
EINECS	Contact for details

Quality Control

Every batch of this advanced chiral compound is produced and analyzed under strict quality control protocols to ensure identity, purity, and enantiomeric excess. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for key parameters such as assay, chiral purity by HPLC, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.