Description

4-Acetyl-2-Fluorobenzeneboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and advanced material chemists for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by introducing the acetyl-fluorophenyl moiety into lead structures.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: An indispensable reagent for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds under mild conditions.
• Library Synthesis: Employed in parallel and combinatorial chemistry for the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-Acetyl-2-Fluorobenzeneboronic Acid Pinacol Ester
CAS No.	1807685-51-3
Molecular Formula	C14H18BFO3
Molecular Weight	264.10 g/mol
Synonyms	2-Fluoro-4-acetylbenzeneboronic acid pinacol ester; (4-Acetyl-2-fluorophenyl)boronic acid pinacol ester; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluorophenyl)ethan-1-one; 4-Acetyl-2-fluorophenylboronic acid pinacol ester; PINACOL (4-ACETYL-2-FLUOROPHENYL)BORONATE; 4-Acetyl-2-fluoro-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
EINECS	Contact for details

Quality Control

Our 4-Acetyl-2-Fluorobenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee reproducible performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.