Description

1-Bromo-3-Nitro-5-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy-substituted nitrobenzene structure, which is critical for modulating the electronic and steric properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for constructing complex biaryl systems.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized nitro- and azo-based dyes and pigments with unique colorfastness and spectral properties.

Basic Information

Product Name	1-Bromo-3-Nitro-5-(Trifluoromethoxy)Benzene
CAS No.	1807151-57-0
Molecular Formula	C7H3BrF3NO3
Molecular Weight	286.00 g/mol
Synonyms	3-Bromo-5-nitro-1-(trifluoromethoxy)benzene; 5-Bromo-1-nitro-3-(trifluoromethoxy)benzene; Benzene, 1-bromo-3-nitro-5-(trifluoromethoxy)-; 1-Bromo-3-nitro-5-(trifluoromethoxy)benzene; 3-Nitro-5-bromophenyl trifluoromethyl ether; 5-Bromo-3-(trifluoromethoxy)nitrobenzene; 3-Bromo-5-(trifluoromethoxy)nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Nitro-5-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.