Description

3-Bromo-2-(Trifluoromethyl)Phenylacetonitrile is a high-value, multi-functional chemical intermediate characterized by its bromine and trifluoromethyl substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced synthesis in demanding research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional polymers due to its unique electronic profile.
• Custom Synthesis and Contract Manufacturing: An essential reagent for fine chemical companies offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	3-Bromo-2-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1807121-68-1
Molecular Formula	C9H5BrF3N
Molecular Weight	264.04 g/mol
Synonyms	2-(3-Bromo-2-(trifluoromethyl)phenyl)acetonitrile; (3-Bromo-2-(trifluoromethyl)phenyl)acetonitrile; α-Cyano-3-bromo-2-(trifluoromethyl)toluene; Benzeneacetonitrile, 3-bromo-2-(trifluoromethyl)-; 1807121-68-1; 3-Bromo-2-trifluoromethylphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP starting materials and aligns with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.