Description

Benzene, 1,3,5-Trifluoro-2-Iodo-4-Methoxy- is a highly functionalized aromatic building block of significant interest in advanced organic synthesis. Its unique combination of fluorine, iodine, and methoxy substituents on a benzene core makes it a versatile precursor for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on the synthesis of novel active ingredients, materials, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, leveraging the iodine for further cross-coupling reactions and the fluorine atoms for modulating bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the fluorine and iodine substituents contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in advanced electronic and display materials.
• Ligand & Catalyst Development: The methoxy and halogen groups provide handles for creating sophisticated ligands used in catalysis and coordination chemistry.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination methodologies, cross-coupling reactions, and structure-activity relationship (SAR) studies.
• Specialty Polymer Modification: Can be incorporated into polymer backbones to impart specific properties like chemical resistance, altered solubility, or unique optical characteristics.

Basic Information

Product Name	Benzene, 1,3,5-Trifluoro-2-Iodo-4-Methoxy-
CAS No.	1806421-84-0
Molecular Formula	C7H4F3IO
Molecular Weight	291.01 g/mol
Synonyms	1,3,5-Trifluoro-2-iodo-4-methoxybenzene; 2-Iodo-1,3,5-trifluoro-4-methoxybenzene; 4-Methoxy-1,3,5-trifluoro-2-iodobenzene; 1,3,5-Trifluoro-4-methoxy-2-iodobenzene; 2-Iodo-4-methoxy-1,3,5-trifluorobenzene; 4-Methoxy-2-iodo-1,3,5-trifluorobenzene; 1806421-84-0; Benzene, 1,3,5-trifluoro-2-iodo-4-methoxy-
EINECS	Contact for details

Quality Control

Our Benzene, 1,3,5-Trifluoro-2-Iodo-4-Methoxy- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for pre-clinical and early-phase clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.