Description

3,4-Difluoro-2-Nitrophenylacetic Acid is a high-value fluorinated aromatic building block characterized by its acetic acid and nitro substituents on a difluorinated benzene ring. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where the fluorine atoms and reactive functional groups enable precise tuning of biological activity and physicochemical properties. It is primarily needed by research institutions and industrial manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology treatments.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Organic Synthesis Building Block: Serves as a versatile substrate for further chemical transformations, including reduction of the nitro group, cyclization reactions, and coupling reactions to create novel heterocycles.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic fluorinated structure.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new synthetic pathways involving fluorinated aromatics.

Basic Information

Item	Details
Product Name	3,4-Difluoro-2-Nitrophenylacetic Acid
CAS No.	1806370-98-8
Molecular Formula	C8H5F2NO4
Molecular Weight	217.13 g/mol
Synonyms	2-(3,4-Difluoro-2-nitrophenyl)acetic acid; (3,4-Difluoro-2-nitrophenyl)acetic Acid; 3,4-Difluoro-2-nitrobenzeneacetic Acid; α-(3,4-Difluoro-2-nitrophenyl)acetic Acid; 1806370-98-8; DFNPA; Difluoronitrophenylacetic Acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Nitrophenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity (by IR and NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.