Description

2,4-Difluoro-6-Methylbenzyl Chloride is a versatile and reactive benzyl chloride derivative, distinguished by its fluorine and methyl substituents. This compound is a critical high-purity building block for advanced synthesis, enabling the introduction of a functionalized benzyl moiety into complex molecular architectures. It is primarily utilized by R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Used in the development of advanced electronic display components and organic light-emitting diodes due to its aromatic and halogenated structure.
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into polymers, such as increased chemical resistance or altered refractive index.
• Chemical Research & Development: Essential reagent for medicinal chemistry and process chemistry for exploring new synthetic routes and creating compound libraries.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2,4-Difluoro-6-Methylbenzyl Chloride
CAS No.	1806333-07-2
Molecular Formula	C8H7ClF2
Molecular Weight	176.59 g/mol
Synonyms	1-(Chloromethyl)-2,4-difluoro-3-methylbenzene; (2,4-Difluoro-6-methylphenyl)methyl chloride; 2,4-Difluoro-6-methylbenzyl chloride; α-Chloro-2,4-difluoro-6-methyltoluene; 2,4-Difluoro-6-methylbenzylchloride; 6-Methyl-2,4-difluorobenzyl chloride; Benzene, 1-(chloromethyl)-2,4-difluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Methylbenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP and ISO 9001 standards where applicable, supporting our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Density (at 20°C)	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.