Description

4-Chloro-2-Fluoro-5-Methylphenylacetic Acid is a high-purity fluorinated and chlorinated aromatic acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the halogenated phenylacetic acid core contributes to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in electronic display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to introduce the substituted phenylacetic acid moiety.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new fluorinated compounds and their physicochemical properties.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Methylphenylacetic Acid
CAS No.	1805227-33-1
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Fluoro-4-chloro-5-methylphenylacetic acid; (4-Chloro-2-fluoro-5-methylphenyl)acetic acid; 5-Methyl-4-chloro-2-fluorophenylacetic acid; 2-Fluoro-4-chloro-α-toluylic acid; 4-Chloro-2-fluoro-5-methylbenzeneacetic acid; α-(4-Chloro-2-fluoro-5-methylphenyl)acetic acid; CAS 1805227-33-1
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Fluoro-5-Methylphenylacetic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with exacting industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.