Description

1-Bromo-2-Chloro-6-(Trifluoromethoxy)Benzene is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique trifluoromethoxy substituent, which imparts desirable electronic and steric properties for advanced chemical synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting complex small molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate for palladium-catalyzed reactions such as Suzuki, Negishi, and Buchwald-Hartwig aminations to construct complex biaryl systems.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of fluorine and fluorinated alkoxy groups on aromatic reactivity and physical properties.

Basic Information

Product Name	1-Bromo-2-Chloro-6-(Trifluoromethoxy)Benzene
CAS No.	1805185-81-2
Molecular Formula	C7H3BrClF3O
Molecular Weight	275.45 g/mol
Synonyms	2-Bromo-1-Chloro-3-(Trifluoromethoxy)Benzene; 6-(Trifluoromethoxy)-1-Bromo-2-Chlorobenzene; 1-Bromo-2-Chloro-6-(Trifluoromethoxy)benzene; 2-Chloro-6-(trifluoromethoxy)bromobenzene; Benzene, 1-bromo-2-chloro-6-(trifluoromethoxy)-; 3-Bromo-2-Chloro(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-6-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.