Description

5-Bromo-2,3-Difluorobenzenesulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive sulfonyl chloride handle and halogenated difluorobenzene core, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Material Science: Used in the development of advanced polymers, liquid crystals, and electronic materials where fluorine and sulfonyl groups impart specific properties.
• Chemical Biology & Proteomics: Acts as a reactive probe or linker in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for bespoke organic synthesis and scale-up projects in fine chemical production.

Basic Information

Product Name	5-Bromo-2,3-Difluorobenzenesulfonyl Chloride
CAS No.	1805119-83-8
Molecular Formula	C6H2BrClF2O2S
Molecular Weight	291.50 g/mol
Synonyms	5-Bromo-2,3-difluorobenzenesulfonyl chloride; 2,3-Difluoro-5-bromobenzenesulfonyl chloride; Benzenesulfonyl chloride, 5-bromo-2,3-difluoro-; 1805119-83-8; 5-Br-2,3-F2-PhSO2Cl
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2,3-Difluorobenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.