Description

2-Bromo-4,5-Difluorobenzodifluoride is a high-value fluorinated aromatic building block, distinguished by its unique combination of bromine and fluorine substituents. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and CNS-active molecules.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the difluorobenzodifluoride moiety enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of high-performance polymers, resins, and specialty coatings with enhanced chemical resistance.
• Liquid Crystal Manufacturing: Employed in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronics: Acts as a building block for electron-transport materials and semiconductors in OLEDs and organic photovoltaics.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.

Basic Information

Item	Detail
Product Name	2-Bromo-4,5-Difluorobenzodifluoride
CAS No.	1804909-69-0
Molecular Formula	C7H2BrF4
Molecular Weight	248.99 g/mol
Synonyms	1-Bromo-2,3-difluoro-4-(trifluoromethyl)benzene; 2,3-Difluoro-4-(trifluoromethyl)bromobenzene; 2-Bromo-1,2-difluoro-3-(trifluoromethyl)benzene; Benzene, 1-bromo-2,3-difluoro-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2,3-difluorobromobenzene; 2-Bromo-4,5-difluoro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,5-Difluorobenzodifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS, NMR (¹H, ¹⁹F) for identity confirmation, to ensure it meets the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.