Description

1-Chloro-5-Fluoro-4-Methoxy-2-Methyl-Benzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a core building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Used in the research and production of specialty electronic chemicals for display technologies and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating high-performance polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and pigments for high-value applications.

Basic Information

Product Name	1-Chloro-5-Fluoro-4-Methoxy-2-Methyl-Benzene
CAS No.	1804881-28-4
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	2-Chloro-4-fluoro-5-methoxytoluene; 4-Chloro-2-fluoro-5-methoxytoluene; 5-Chloro-1-fluoro-2-methoxy-4-methylbenzene; 1-Chloro-5-fluoro-4-methoxy-2-methylbenzene; 2-Methyl-1-chloro-5-fluoro-4-methoxybenzene; 4-Methoxy-2-methyl-1-chloro-5-fluorobenzene; Benzene, 1-chloro-5-fluoro-4-methoxy-2-methyl-
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Fluoro-4-Methoxy-2-Methyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.