Description

5-Chloro-1,2-Difluoro-3-Methoxybenzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which provides strategic sites for further functionalization, making it an essential intermediate in the development of complex molecules. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethoxybenzene core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro and fluoro substituents enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic compounds used in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalytic systems.
• Polymer Modification: Incorporated into polymer backbones to impart specific properties like chemical resistance, thermal stability, or altered solubility.
• Chemical Research (R&D): A versatile scaffold for medicinal chemistry and material science research to explore new chemical entities and their properties.

Basic Information

Item	Detail
Product Name	5-Chloro-1,2-Difluoro-3-Methoxybenzene
CAS No.	1804875-58-8
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	3-Methoxy-5-chloro-1,2-difluorobenzene; 1-Chloro-2,3-difluoro-5-methoxybenzene; 5-Chloro-1,2-difluoro-3-methoxy-benzene; Benzene, 5-chloro-1,2-difluoro-3-methoxy-; 1804875-58-8
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-1,2-Difluoro-3-Methoxybenzene is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.