Description

Benzonitrile, 2-Bromo-5-(Trifluoromethoxy)- is a high-value, multi-functional aromatic nitrile building block distinguished by its bromine and trifluoromethoxy substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into polymer backbones to impart specific characteristics like chemical resistance, thermal stability, or unique optical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) for complex molecule assembly.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	Benzonitrile, 2-Bromo-5-(Trifluoromethoxy)-
CAS No.	1804402-93-4
Molecular Formula	C8H3BrF3NO
Molecular Weight	266.02 g/mol
Synonyms	2-Bromo-5-(trifluoromethoxy)benzonitrile; 2-Bromo-α,α,α-trifluoro-p-cresol cyanide; 5-(Trifluoromethoxy)-2-bromobenzonitrile; 2-Bromo-5-trifluoromethoxybenzonitrile; 2-Bromo-5-(trifluoromethoxy)phenyl cyanide; Benzonitrile, 2-bromo-5-(trifluoromethoxy)-; [2-Bromo-5-(trifluoromethoxy)phenyl]carbonitrile
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 2-Bromo-5-(Trifluoromethoxy)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality system is designed to support cGMP and ISO 9001 standards, making this material suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to the compound's sensitivity to moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.