Description

Benzene, 2-Fluoro-1,3-Diiodo-5-Methoxy- is a highly functionalized halogenated aromatic building block, identified by CAS number 1803829-27-7. This compound is valued for its unique substitution pattern, offering multiple reactive sites for advanced synthetic transformations in pharmaceutical and materials chemistry. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and iodinated aromatic cores for bioactivity or as a radiolabeling synthon.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the fluorine and iodine atoms contribute to metabolic stability and binding affinity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its halogenated structure can influence dielectric properties and molecular alignment.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), leveraging the iodine atoms for selective functionalization.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reaction methodologies and creating libraries of novel chemical entities.
• Ligand & Catalyst Preparation: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	Benzene, 2-Fluoro-1,3-Diiodo-5-Methoxy-
CAS No.	1803829-27-7
Molecular Formula	C7H5F I2O
Molecular Weight	377.92 g/mol
Synonyms	1,3-Diiodo-2-fluoro-5-methoxybenzene; 2-Fluoro-1,3-diiodo-5-methoxybenzene; 5-Methoxy-2-fluoro-1,3-diiodobenzene; 3-Fluoro-2,6-diiodoanisole; 2,6-Diiodo-3-fluoroanisole; F-Diiodo-Methoxy-Benzene; Benzene, 1,3-diiodo-2-fluoro-5-methoxy-
EINECS	Contact for details

Quality Control

Our Benzene, 2-Fluoro-1,3-Diiodo-5-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.